Like other phenanthrene derivatives, dihydrocodeine is especially metabolised while in the liver with the resultant metabolites becoming excreted largely within the urine.
Dry mouth Test chewing sugar-free gum or sucking sugar-free sweets. You may also acquire or a health care provider may well prescribe a man-made saliva substitute to keep your mouth moist. This comes to be a spray, gel or lozenge and can be purchased from the pharmacy.
Concomitant usage of Dihydrocodeine tablets and sedative medicines for instance benzodiazepines or associated drugs raises the chance of drowsiness, problems in breathing (respiratory depression), coma and should be lifethreatening.
Aspirin, caffeine, and dihydrocodeine combination is utilised To ease pain extreme more than enough to need opioid treatment and when other pain medicines did not work properly ample or can't be tolerated.
Swallow the tablets with a drink of water. Dihydrocodeine need to preferably to taken just after food items, as This may help protect against feelings of sickness which can from time to time happen with the initial couple doses.
Reporting of adverse reactions Reporting suspected adverse reactions after authorisation of your medicinal product is very important. It will allow ongoing monitoring on the gain/hazard balance from the medicinal product.
Make sure you understand how to take this medication and what other drugs you'll want to stay away from taking with it. See also Drug Interactions section. Get medical help instantly if any of those extremely really serious side effects arise: slow/shallow respiration, uncommon lightheadedness, serious drowsiness/dizziness, issue waking up.
Dihydrocodeine is available in Japan as tablets which contain two.5 mg of dihydrocodeine phosphate and caffeine, the decongestant d,l-methylephedrine HCl, as well as antihistamine chlorpheniramine, and packets of granules which effervesce like Alka-Seltzer with 10 mg of dihydrocodeine with lysozyme and chlorpheniramine, marketed for OTC sale as New Bron Answer-ACE.
Common use during pregnancy could cause drug dependence within the foetus, leading to withdrawal symptoms during the neonate.
Sedative medicines like benzodiazepines or similar drugs: The concomitant use of opioids with sedative medicines for instance benzodiazepines or connected drugs improves the danger website of sedation, respiratory depression, coma and Loss of life thanks to additive CNS depressant outcome. The dose and duration of concomitant use needs to be constrained (see section four.four).
Applying alcohol or tobacco with certain medicines might also trigger interactions to occur. The subsequent interactions have been chosen on The premise of their possible significance and they are not automatically all-inclusive.
This product may contain inactive ingredients, which may cause allergic reactions or other challenges. Talk to your pharmacist For additional information.
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This medicine is definitely an opioid painkiller. There is a significant chance of addiction when taking this medicine, particularly if utilised long-term. The Medicines and Healthcare products Regulatory Agency (MHRA) has issued new guidance for men and women prescribed an opioid painkiller.